Mitochondria and Cancer (Paperback)

Mitochondria and Cancer By Keshav Singh (Editor), Leslie Costello (Editor) Cover Image
By Keshav Singh (Editor), Leslie Costello (Editor)
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Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration of nuclear genes encoding mitochondrial proteins. This book, Mitochondria and Cancer, edited by Keshav K. Singh and Leslie C. Costello, presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer, discusses the clinical implications of mitochondrial defects in cancer, and as unique cellular targets for novel and selective anti-cancer therapy.

Product Details
ISBN: 9781441927385
ISBN-10: 1441927387
Publisher: Springer
Publication Date: October 29th, 2010
Pages: 289
Language: English